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Positron emission tomography (PET) for assessing myocardial viability

Positron emission tomography (PET) for assessing myocardial viability

Positron emission tomography (PET) is usually taken as the gold standard for assessment of myocardial viability. PET scan with 13NH3 (ammonia) gives the perfusion while 18FDG (fluorodeoxyglucose) shows the metabolic activity of the myocardium. A mismatch between perfusion and metabolism whereby underperfused region of myocardium is shown to have active metabolism, is an indicator of myocardial viability.

The most important limitation of PET is its high cost and limited availability. It has some radiation risk when compared to echocardiography and cardiac magnetic resonance (CMR) imaging.

Important advantages of PET are that the validity is well established and it has an excellent sensitivity. PET can be done in patients with cardiac implantable electronic devices (CIED), while CMR is not suitable in that situation. Compared to single photon emission computed tomography (SPECT), PET has a better spatial and temporal resolution with better quality of pictures and less radiation risk.


MCQs in Medicine - Cardiovascular System is based on undergraduate medical curriculum. Though the questions are aimed at basic post graduate entrance examinations, candidates taking competitive exams at the post graduate exit level may also find them useful, especially the explanations for the answers. Undergraduate medical students will find them useful for answering MCQ tests in their regular exams. More than just answering MCQs, the explanations will improve the knowledge and understanding about the conditions discussed.Medicine MCQs - Cardiovascular System Kindle Edition: Click Here for a Preview Comments and suggestions are most welcome.