Elevated LDL cholesterol – Cardiology MCQ

Which of the following is not a cause for elevated LDL cholesterol ?

a) Pregnancy

b) Hyperthyroidism

c) Uncontrolled diabetes mellitus

d) Obesity

Correct answer: b) Hyperthyroidism

Hypothyroidism is associated with elevated LDL cholesterol and triglycerides. Cholesterol and triglycerides rise progressively through out pregnancy. It may be noted that treatment with statins, niacin and ezetimibe are contraindicated in pregnancy and lactation. Triglycerides are elevated in poorly controlled diabetes mellitus. Both triglycerides and cholesterol are elevated in obesity [1].

Reference
1. Stone NJ et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63:2889-934.

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