When can regression of clubbing occur in cyanotic congenital heart disease?

When can regression of clubbing occur in cyanotic congenital heart disease?

Regression of clubbing in cyanotic congenital heart disease can occur following surgical correction of CCHD. When surgical correction is done relatively early in life, cyanosis disappears and clubbing gradually subsides.

It has even been reported after surgical palliation by right ventricular outflow tract augmentation in a six year old with Tetralogy of Fallot. Complete regression of extreme digital clubbing was noted 10 months after surgery. The child underwent successful complete repair 12 months after palliative surgery [1].

Reference

1. Bertram H, Jack T, Schranz D, Breymann T, Wessel A, Yelbuz TM. Images in cardiovascular medicine. Rapid regression of classic clinical signs of cyanosis accompanied by disappearing major aortopulmonary collaterals after surgical palliation only in a 6-year-old girl with tetralogy of fallot. Circulation. 2008 Oct 14;118(16):e665-6. doi: 10.1161/CIRCULATIONAHA.108.788257. PMID: 18852372.