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Category Archives: General
Potential adverse events after ICD implantation
Implantable cardioverter defibrillators (ICD) are life saving devices used for treatment of life threatening ventricular arrhythmias and averting sudden cardiac death. Some of the rare adverse events which [..]
Functional mitral regurgitation (FMR)
Functional mitral regurgitation (FMR) occurs due to non-coaptation of mitral leaflets in the setting of left ventricular dilatation. It can occur in cardiomyopathies of both ischemic and idiopathic [..]
Over 90% freedom from severe MR twenty years after mitral valve repair
90.7% freedom from recurrent severe mitral regurgitation was documented at twenty years after mitral valve repair in a study by David TE et al [Late outcomes of mitral [..]
Radiation associated heart disease
Radiation associated heart disease is more noted in survivors of breast cancer and Hodgkin’s disease who had undergone radiotherapy with incidental radiation to the heart. The risk is [..]
Pacemaker implantation safe in nonagenarians
Mandawat A and colleagues [Safety of Pacemaker Implantation in Nonagenarians. An Analysis of the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample. Circulation. 2013;127:1453-1465.] retrospectively analyzed the data of [..]
Long term mortality similar for mechanical vs bioprosthetic valves in older patients- New study
J. Matthew Brennan and associates from Duke Clinical Research Institute [Long-Term Safety and Effectiveness of Mechanical versus Biologic Aortic Valve Prostheses in Older Patients: Results from the Society [..]
One year results of on pump and off pump CABG similar – New study
A large randomized clinical trial involving over four thousand seven hundred patients from seventy nine centres across nineteen countries has been published in NEJM [Lamy A et al. [..]
Calmodulin gene mutation producing life threatening QT prolongation
Lia Crotti and colleagues along with Peter Schwartz [Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants. Circulation. 2013; 127: 1009-1017.] , the pioneer in studies on congenital [..]
When to consider cardioembolic stroke?
Following features may help in thinking of a cardioembolic etiology for stroke: Sudden onset to maximal neurological deficit Decreased level of consciousness at onset Wernicke’s aphasia or global [..]
Ivabradine
Ivabradine is a selective inhibitor of the Funny Current (If) or the pacemaker current in the sinoatrial (SA) node. This results in pure heart rate reduction. This can [..]