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Author Archives: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin
Clopidogrel and statin releoad protects against early cerebral ischemic events
ARMYA-9 CAROTID study [Patti G et al. Strategies of Clopidogrel Load and Atorvastatin Reload to Prevent Ischemic Cerebral Events in Patients Undergoing Protected Carotid Stenting: Results of the [..]
Implantable loop recorder
Implantable loop recorder is an implantable cardiac electronic device which is usually implanted subcutaneously in the pectoral region like a pacemaker. It monitors the electrocardiogram continuously, but transfers [..]
Calmodulin gene mutation producing life threatening QT prolongation
Lia Crotti and colleagues along with Peter Schwartz [Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants. Circulation. 2013; 127: 1009-1017.] , the pioneer in studies on congenital [..]
Brugada Syndrome 1,2,3,4,5,6,7,8
Brugada syndrome is an inherited arrhythmogenic syndrome with life threatening ventricular arrhythmias, right bundle branch like pattern and ST segment elevation in right precordial leads. The first gene [..]
Progression of AF less likely with rhythm control strategy
Progression of atrial fibrillation (AF) can be defined as a change from paroxysmal atrial fibrillation to persistent/permanent atrial fibrillation. Progression of AF is less likely if a rhythm [..]
Vernakalant for the management of recent onset AF
Vernakalant is a rapidly acting drug useful in the treatment of recent onset atrial fibrillation. Unlike amiodarone which is a slow acting drug, vernakalant is a rapidly acting [..]
When to consider cardioembolic stroke?
Following features may help in thinking of a cardioembolic etiology for stroke: Sudden onset to maximal neurological deficit Decreased level of consciousness at onset Wernicke’s aphasia or global [..]
Ivabradine
Ivabradine is a selective inhibitor of the Funny Current (If) or the pacemaker current in the sinoatrial (SA) node. This results in pure heart rate reduction. This can [..]
Tolvaptan: Vasopressin Antagonist
Tolvaptan is vasopressin antagonist which acts on the V2 receptors in the renal tubules. Activation of V2 receptors increases water permeability in the renal collecting duct resulting in passive [..]
ECG Quiz 8
What is the rhythm? a) Sinus rhythm b) Low atrial rhythm c) Idioventricular rhythm d) None of the above Answer: b) Low atrial rhythm ECG showing negative P [..]