Chest compression rate affect return of spontaneous circulation, not survival to hospital discharge

Idris AH and associates [Relationship Between Chest Compression Rates and Outcomes From Cardiac Arrest. Circulation. 2012; 125: 3004-3012] have found that chest compression rates during cardiopulmonary resuscitation (CPR) affect return of spontaneous circulation, but not survival to hospital discharge. In a study involving 3098 subjects with out of hospital cardiac arrests, return of spontaneous circulation peaked at a chest compression rate of around 125 per minute. This is higher than the standard CPR recommendation of 100 per minute chest compressions. Though the return of spontaneous circulation was higher at higher rates of chest compression, this did not translate into higher rates of survival up to hospital discharge, which is a more desirable outcome.

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