Cardiophile MD

Angiotensin II receptors

Angiotensin II receptors Angiotensin II receptors are a group of G-protein coupled receptors. They are an important part of the renin-angiotensin system, involved in signal transduction. AT1 receptor: stimulation produces vasoconstriction and is pro-inflammatory....

Endothelium derived hyperpolarising factor (EDHF)

Endothelium derived hyperpolarising factor (EDHF) Endothelium derived hyperpolarising factor (EDHF) is one of the three endothelium-derived relaxing factors (EDRFs), others being nitric oxide (NO) and prostacyclin (PGI2). EDHF as the name implies, hyperpolarizes the...

What is chronic rheumatic carditis?

What is chronic rheumatic carditis? Rheumatic carditis lasting more than 6 months is considered as chronic rheumatic carditis. Evidence of recent streptococcal infection as an essential criteria for the diagnosis of rheumatic carditis cannot...

Nitric oxide synthase – NOS1, NOS2, NOS3

Nitric oxide synthase Three important varieties of nitric oxide synthase involved in the synthesis of nitric oxide can be seen in the human system. They are neuronal, inducible and endothelial varieties. nNOS: neuronal nitric oxide...